Copovidone Pharmaceutical Excipients with Many Uses
Delivery term:The date of payment from buyers deliver within days-
Price:
Negotiable
- minimum:
- Total supply:
-
Delivery term:
The date of payment from buyers deliver within days
-
seat:
Zhejiang
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Validity to:
Long-term effective
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Last update:
2017-12-25 05:51
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Browse the number:
394
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- Contactaixin:
Contactaixin:
hzlanbo2017(Mr.)
- Email: telephone: phone:
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Area:
Zhejiang
Address:3-405 B, Xi Gang Xing Jie No.206 Zhenhua Road,San Dun, Xihu District, Hangzhou, Zhejiang, China
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SUNVIDONE® VA
Synonyms: Copovidone;Copolyvidone; PVP/ VAc
CTFA/INCI:VP/VA copolymer
CAS No.: [25086-89-9]
Trade Name: Sunvidone® VA
SUNVIDONE® VA is a vinylpyrrolidone-vinyl acetate copolymer that is soluble both in water and in alcohols.
It is used in the pharmaceutical industry as binders, granulating agents, retarding agents and film.
forming agents in drugs.
SPECIFICATION
SUNVIDONE® VA meets the requirements of the latest USP/NF, Ph.Eur. and JPE | |||
Appearance of solution (10%) |
BY5, B5 min. |
Heavy metals |
20ppm max |
Aldehydes |
500ppm max. |
Loss on drying |
5.0% max |
Peroxides |
400ppm max. |
sulphated ash |
0.1% max |
Hydrazine |
1ppm max. |
K value |
25.2-30.8 |
Monomers |
0.1% max. |
Ethenyl acetate |
35.3%-42.0% |
Impurity A |
0.5% max. |
Nitrogen |
7.0%-8.0% |
CHARACTERISTICS
White or slightly yellowish, free-flowing powder with a faint characteristic odor and practically no taste.
Sunvidone® VA readily dissolves in all hydrophilic solvents. Solutions of more than 10% concentration can be prepared in: water; ethanol; isopropanol; methylene chloride; glycerol; propylene glycol; It is less soluble in: ether; cyclic, aliphatic and alicyclic hydrocarbons.
APPLICATIONS
• Binder for tablets and granules Dry binder for direct compression Wet granulation |
Sunvidone® VA is an excellent binder for tablets and granules. Between 2% and 5%, as a proportion of the final weight of the preparation, is usually used. |
• Film-coating |
Sunvidone® VA forms films that are soluble at all pH values. |
• Subcoating |
Sunvidone® VA is used in sugar-coating to improve the |
• Sugar-coating |
adhesion of the coating to the surface of the tablet core and to |
• Sprays |
increase the capacity of the coating solution for pigments and |
• Controlled-release preparations |
improve their dispersibility. |
PACKAGES 20KG or 25KG net in fiber drum or PP drum